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Although it is widely accepted, that many chronic diseases are multifactorial in origin, they share oxidative stress as a common denominator

A multidisciplinary approach and effective communication with the family are essential

Amount of weight loss: Weight loss also varied a lot in the trial, so researchers compared the health effects in those with a little versus a lot of relative weight loss

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Lesions which are small (15 mm), uniformly pigmented, brown to black, sharply circumscribed macules may be found anywhere on the integument, the conjunctivae, and mucocutaneous orifices (Fig